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Categories: giantSciencevirus

Giant virus has evolved its own kind of CRISPR to destroy invaders

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By Michael Le Page

Large viruses may have sophisticated immune systems

MEHAU KULYK/SCIENCE PHOTO LIBRARY

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The mimivirus is so enormous it has its own kind of CRISPR-like immune system to defend against the smaller viruses that attack it. A team in France has confirmed how it works by transferring the entire system to a bacterium and tweaking it to destroy a different target.

While CRISPR has become famous as a tool geneticists can use for editing genomes, it evolved in bacteria as a way of defending against viruses. The bacteria “cannibalise” bits of DNA from the viruses that attack them and add this …

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