Sydney researchers awarded over $42 million in NHMRC Investigator Grants

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27 ground-breaking research projects receive funding
The University of Sydney has been awarded over $42 million in 2024 NHMRC Investigator Grants funding to research some of the nation’s greatest health challenges.

University of Sydney researchers have been granted more than $42 million over five years in the 2024 National Health and Medical Research Council (NHMRC) Investigator Grants.

A total of 27 projects have secured fundings to help solve some of the nation’s most pressing problems from across the spectrum of health and medical research.

The projects awarded range from the identification of molecular mechanisms initiating and propagating neurodegenerative diseases to tailoring treatment to improve outcome for ovarian cancer patients.

NHMRC Investigator Grants support the four pillars of health and medical research – biomedical, clinical, public health and health services research – and researchers at all career stages.

The scheme is designed to allow flexibility to pursue important new research directions, to form collaborations, and to foster innovative and creative research.

“The Investigator Grant scheme provides the highest-performing researchers with the flexibility to pursue important new research directions as they arise,” said Deputy Vice-Chancellor (Research) Professor .

“This impressive and diverse array of projects demonstrates the University of Sydney’s outstanding capability to foster innovative and creative research focused on addressing the most pressing challenges in health and medicine by creating new knowledge, improving treatments and helping to make our health system even better.

“I am extremely proud to see so many of our researchers recognised for the important role they are playing to improve health outcomes for people everywhere.”

Full list of NHMRC Investigator Grants to the University of Sydney​

  • Professor – Cell type and organelle specific identification of molecular mechanisms initiating and propagating neurodegenerative diseases ($3 million)
  • Professor – Targeting β-cells for diabetes therapy ($2.9 million)
  • Professor – Management of musculoskeletal pain: testing treatment effectiveness and reducing medication-related harm ($2.9 million)
  • Associate Professor Veronica Matthews – Strengthening primary health systems through Australian Indigenous paradigms: self-governance for healthy Country and community wellbeing ($2.8 million)
  • Professor – Tailoring treatment to improve outcome for ovarian cancer patients ($2.7 million)
  • Associate Professor – Neuroimaging, neural models, and neurobiology: A fresh look at dementia ($2.4 million)
  • Dr – Paving the way towards a new national screening program for type 1 diabetes and coeliac disease for all Australian children ($1.6 million)
  • Dr – Discovery of a novel dopamine circuit that uniquely contributes to methamphetamine use disorder ($1.6 million)
  • Dr – Opioid stewardship for patients undergoing hip and knee replacements ($1.6 million)
  • Dr – Don’t blow it: Harnessing an effective and scalable drug prevention model to curb youth vaping ($1.6 million) ($674,400)
  • Dr – Rising temperatures, rising risks: Preventing heat-induced rises in cardiovascular disease ($674,400)
  • Dr – Risk prediction models for time to event data: translating clinical trials into practice ($674,400)
  • Dr – Harnessing the power of the human brain microphysiological system as a model for neuroinflammation, viral infections and pre-clinical therapeutic screening ($674,400)
  • Dr – Plugging the sodium leak in severe neurodevelopmental disorders ($674,400)
  • Dr – Profiling of immunotherapy resistant tumours to inform treatment selection and drug discovery for patients with advanced cancer ($674,400)
  • Dr – Dissecting the cancer ecosystem as a precision medicine approach towards improving patient outcomes with high-risk melanoma ($674,400)
  • Dr – Nanocarriers for oral biologic delivery ($674,400)
  • Dr Shania Liu – Reducing the harms associated with inappropriate opioid use before spine surgery ($674,400)
  • Dr – Making equitable decisions: Embedding appropriate and robust methods for exploring equity impacts in health decision-making processes ($674,400)
  • Dr – The dangerous path of self-medicating postpartum stress and anxiety with alcohol: Intervening early to improve the health and wellbeing of both mother and child ($674,400)
  • Dr Aleksandra Petrovic Fabijan – Phage therapy: translating research evidence into clinical application ($632,308)
  • Associate Professor – NeoPlatform: Neoadjuvant translational research platform to predict, monitor and enhance response to immunotherapy ($454,385)
  • Dr – At risk: A novel neurophysiological approach to biomarkers in neurodegeneration ($1.6 million)
  • Professor David Beard – Strategic development of a trial culture for surgical innovation and evaluation: A node catalyst model ($2 million)
  • Professor – Complementary studies of HIV and Herpes Simplex Viral infection of genital mucosa and the mechanism of action of systemically delivered vaccines ($3m)
  • Professor – Ensuring Australians with back pain receive the right care ($3 million)
  • Professor Cameron Turtle – Identifying and overcoming mechanisms of failure of CD19 CAR-T cell immunotherapy for large B cell lymphoma ($2.9 million)
 
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